Ternary inclusion complex of docetaxel using ß-cyclodextrin and hydrophilic polymer: Physicochemical characterization and in-vitro anticancer activity
نویسندگان
چکیده
HER-2 targeted immunonanoparticles for breast cancer chemotherapyRitu Dhankar, Parmender Rathee, Arvind K Jain, Sahil Arora, Murugesan Senthil Kumar, Goutam Rath, Ajit Kumar Saxena, P.R. Sharma, Gousia Chashoo, Amit K. Goyal
منابع مشابه
Preparation, Physicochemical Characterization and In-vitro Dissolution Studies of Diosmin-cyclodextrin Inclusion Complexes
Diosmin, a vascular-protecting agent, is practically insoluble in water, and its oral absorption is limited by its extremely low dissolution rate. In this study, β-cyclodextrin (βCD) and 2-hydroxypropyl-β-cyclodextrin (HPβCD) were obtained to improve the solubility and dissolution rate of diosmin. Phase solubility studies of diosmin with βCD and HPβCD in distilled water were conducted to charac...
متن کاملPreparation, Physicochemical Characterization and In-vitro Dissolution Studies of Diosmin-cyclodextrin Inclusion Complexes
Diosmin, a vascular-protecting agent, is practically insoluble in water, and its oral absorption is limited by its extremely low dissolution rate. In this study, β-cyclodextrin (βCD) and 2-hydroxypropyl-β-cyclodextrin (HPβCD) were obtained to improve the solubility and dissolution rate of diosmin. Phase solubility studies of diosmin with βCD and HPβCD in distilled water were conducted to charac...
متن کاملPhysicochemical characterization and cytotoxic activity evaluation of hydroxymethylferrocene:β-cyclodextrin inclusion complex.
An inclusion complex of hydroxymethylferrocene (FeMeOH) with β-cyclodextrin (β-CD) was prepared in the solid state by different techniques such as physical mixture, coprecipitation, kneading and freeze-drying. The formation of the inclusion complex was confirmed by X-ray Powder Diffractometry and Fourier Transform-Infrared spectroscopy. In aqueous solution, the 1:1 stoichiometry was established...
متن کاملpreparation, physicochemical characterization and in-vitro dissolution studies of diosmin-cyclodextrin inclusion complexes
diosmin, a vascular-protecting agent, is practically insoluble in water, and its oral absorption is limited by its extremely low dissolution rate. in this study, β-cyclodextrin (βcd) and 2-hydroxypropyl-β-cyclodextrin (hpβcd) were obtained to improve the solubility and dissolution rate of diosmin. phase solubility studies of diosmin with βcd and hpβcd in distilled water were conducted to charac...
متن کاملPhysicochemical Characterization, in vitro Release and Permeation Studies of Respirable Rifampicin-Cyclodextrin Inclusion Complexes
The inclusion complexes of rifampicin with sucralose and beta-cyclodextrins were prepared by spray drying method. The complexes were characterized by size analyses, scanning electron microscopy, differential scanning calorimetry and x-ray diffraction methods. The results indicated the amorphous nature of resultant products. The solubility, in vitro release and skin permeation of the drug were e...
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ژورنال
عنوان ژورنال: journal of applied pharmaceutical science
سال: 2022
ISSN: ['2231-3354']
DOI: https://doi.org/10.7324/japs.2022.121216